My setup is Win 10 with two, different sized monitors (I hear it might be important). It does not draw or run the code from gestures. I had not done any changes lately and I think WindowsUpdate was run recently..
I tried enable/disable, logoff/logon, run as admin and reinstall but nothing so far.
Hmm, these type of situations are very difficult to troubleshoot. You can try emailing me you StrokesPlus.xml (usually under you AppData\Roaming\StrokesPlus folder and I can take a look. Of course, you can also try moving those files out of the folder and reinstalling, since the setup won't overwrite them, and if there's a problem in one of those files it would persist after reinstalling.